Peculiarities of lipid peroxidation processes in the body of cats with urinary tract diseases and their correction with commercial feeds

Authors

  • Olga Andreevna Vorontsova Saratov State Agrarian University named after N.I. Vavilov
  • Nikolay Alexandrovich Pudovkin Saratov State Agrarian University named after N.I. Vavilov
  • Vladimir Vasilievich Salautin Saratov State Agrarian University named after N.I. Vavilov
  • Sergey Dmitrievich Klyukin Saratov State Agrarian University named after N.I. Vavilov

DOI:

https://doi.org/10.28983/asj.y2021i4pp37-40

Keywords:

lipid peroxidation, malondialdehyde, diene conjugates, catalase, cats, lower urinary tract diseases

Abstract

The article presents the results of studies on the effect of commercial food on the processes of free radical oxidation of lipids in the body of cats with urinary tract pathology. It has been found that the concentration of diene conjugates in the blood serum of sick animals increases significantly by 15.1 - 36.7% relative to healthy ones. The MDA content in the blood serum of healthy animals was 6.05 ± 0.28 nmol / g. In animals with urolithiasis, this indicator increased by about 2 times. When feeding with commercial food and homemade food, LPO processes normalize, which is most pronounced on the 21st day. The average activity of catalase in the blood serum of sick animals was increased from 30.6% to 40.2% relative to healthy ones (15.15 ± 0.61 ?mol / ml). After feeding with therapeutic and prophylactic fodders, by the 7th day, the catalase activity did not significantly decrease compared to the initial level, but remained higher than in control animals by 19.6% - 37.1%. On the 14th day, the catalase activity did not change significantly compared with the 7th day and was higher than the control values by 21.5% - 27.5%.

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Author Biographies

Olga Andreevna Vorontsova, Saratov State Agrarian University named after N.I. Vavilov

Post-graduate Student

Nikolay Alexandrovich Pudovkin, Saratov State Agrarian University named after N.I. Vavilov

Doctor of Biological Sciences

Vladimir Vasilievich Salautin, Saratov State Agrarian University named after N.I. Vavilov

Doctor of Veterinary Sciences

Sergey Dmitrievich Klyukin, Saratov State Agrarian University named after N.I. Vavilov

Assistant

References

Клинико-биохимическое изучение эффективности Миртазапина при лечении идиопатического цистита котов/ О.А. Воронцова [и др.] // Вестник Бурятской ГСХА. – 2019. – № 4. – С.12–18.

Метод определения активности каталазы / М.А. Королюк [и др.] // Лабораторное дело. – 1988. – № 1. – С. 16–19.

Мутация С1167т в гене каталазы и развитие нейропатии при сахарном диабете 1 типа / Е.В. Зотова[и др.]// Сахарный диабет. – 2000. – №2. – С. 7–8.

Осипова Ю.С., Квочко А.Н. Ретроспективный анализ заболеваний мочевывыделительной системы кошек в регионе Кавказские Минеральные Воды //Аграрный научный журнал. – 2015. – № 6. – С. 24–28.

Применение «Уроцистона» при экспериментальном моделировании цистита / С.Г. Глущенко [и др.] // Вестник АПК Ставрополья. – 2018. – №4(32). – С. 36–41.

Рязанцева Л.Т. Ферменты-антиоксиданты: структурно-функциональные свойства и роль в регулировании метаболических процессов // Вестник Воронежскогогос. техн. ун-та. – 2011. –Т.7. – № 2. – С. 126–129.

Стальная И.Д., Гаришвили Т.Г. Метод определения малоновогодиальдегида с помощью тиобарбитуровой кислоты // Современные методы в биохимии. – М.: Медицина, 1977. – С. 66–67.

Стальная И.Д., Гаришвили Т.Г. Методы определения диеновой конъюгации ненасыщенных высших жирных кислот // Современные методы в биохимии. – М.: Медицина, 1977. – С. 67–68.

Vazin N.D. Molecular mechanisms of lipid disorders in nephrotic syndrome // Kidney Int, 2003, Vol. 63, Р.1964–1976.

Published

2021-04-22

Issue

Section

Zootechnics and veterinary

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